Cough/Cold
NyQuil
Acetaminophen/Dextromethorphan/Doxylamine · 325/15/6.25 mg · liquid · qty 1
Nighttime cold & flu relief.
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Common uses & information
NyQuil is a brand of Acetaminophen/Dextromethorphan/Doxylamine, a cough/cold medication supplied as liquid in a 325/15/6.25 mg strength. It is commonly used for nighttime cold & flu relief.
An FDA-approved generic (Acetaminophen/Dextromethorphan/Doxylamine) is available and typically costs less than the brand — compare both cash prices in the table above before you fill.
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Price summary
| Form | Class | Brand avg | Generic avg | Savings |
|---|---|---|---|---|
| liquid 325/15/6.25 mg | OTC | $13.99 — generic is cheaper, see recommendation | $5.99Generic recommended | 57% |
Clinical information
Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →
Manufacturer & patient assistance programs
FAQ
Is generic Acetaminophen/Dextromethorphan/Doxylamine the same as NyQuil?
Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.
How much can I save by choosing the generic?
On average $8.00 per fill (57% off the brand price). Savings vary by pharmacy — see live prices above.
Do I need insurance to get this price?
No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.
How often is this price updated?
At minimum every 72 hours. Many sources refresh every few hours.
Related medications
Compare NyQuil with other options and see the generic price.
Cheapest NyQuil alternatives
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Information for general comparison only. Not medical advice. Confirm with your pharmacist.
