Prescription Prices in South Carolina — 2026

Overview

Prescription cash prices in South Carolina vary widely — the same drug can cost 2-8x more at different pharmacies just miles apart. Use this page to compare the pharmacies that serve South Carolina and find the lowest cash price before you fill.

Pharmacies serving South Carolina

• Mail-order

  Mark Cuban Cost Plus

  Ships generics nationwide at a transparent cost-plus markup.

• Coupon network

  GoodRx Coupon

  Free coupons accepted at most US pharmacies — often beats insurance on generics.

• Warehouse

  Costco Pharmacy

  Membership not required to use the pharmacy by federal law. Strong generic cash prices.

• Big-box

  Walmart Pharmacy

  $4 / $10 generic program covers hundreds of common drugs.

• Big-box

  CVS Pharmacy

  Widest US footprint. Cash prices vary; coupons help.

• Big-box

  Walgreens

  Nationwide chain; compare cash price against coupon networks before filling.

• Independent

  Local independent pharmacies

  Often the most flexible on cash-pay price. Always worth a call.

• Grocery

  Publix Pharmacy

  Free 14-day supply of select antibiotics and metformin.

• Grocery

  Kroger Rx

  Kroger Savings Club unlocks lower cash prices on many generics.