Savings guide
How to Save on Orkambi (Lumacaftor/Ivacaftor) 200mg/125mg
Current lowest price
The lowest cash price we track for Orkambi 200mg/125mg is about $0.35. Prices update as pharmacies change them — see the full live table below.
Compare live Orkambi prices →Generic vs brand
The FDA requires generic medications to demonstrate bioequivalence, meaning the same active ingredient, strength, dosage form, and route of administration as the brand-name product. A generic version of Lumacaftor/Ivacaftor works the same way in the body as brand Orkambi.
Because generics don't carry the original research and marketing costs, they usually cost far less while meeting the same FDA quality, strength, and purity standards. Read our generic vs. brand explainer →
Cheapest pharmacies for Orkambi
- Kroger Rx$0.35
Steps to save on Orkambi
1. Compare cash prices
Compare Orkambi cash prices across every US pharmacy before you fill — the same drug can cost several times more at one counter than another.
2. Check for a generic
Ask whether a generic or therapeutic alternative is available — generics are FDA-rated therapeutically equivalent and usually cost far less.
3. Apply a pharmacy coupon
Use a free discount coupon (such as GoodRx) at the pharmacy counter. Coupons and insurance cannot be combined, so compare the cash-coupon price against your copay.
4. Ask about patient assistance
Ask the manufacturer and nonprofit foundations whether a patient-assistance or copay program covers this medication if you qualify.
5. Try mail-order
Mail-order pharmacies like Mark Cuban Cost Plus often price 90-day generic supplies below retail. Confirm the drug is in their catalog first.
FAQ
How can I save money on Orkambi?
Compare cash prices across pharmacies, ask about generic Lumacaftor/Ivacaftor, use a free coupon, and check for a manufacturer assistance program. Prices for the same drug vary widely between pharmacies.
Is there a generic version of Orkambi?
Orkambi's active ingredient is Lumacaftor/Ivacaftor. Ask your pharmacist whether a generic or lower-cost therapeutic alternative is currently available for you.
Does Orkambi have a manufacturer savings program?
We don't have a verified manufacturer savings program on file for Orkambi. Compare pharmacy cash prices and coupons, which anyone can use without enrollment.
Which pharmacy has the cheapest Orkambi?
Right now Kroger Rx shows one of the lowest cash prices, around $0.35. Mark Cuban Cost Plus and Costco are frequently the cheapest for generics.
Do I need insurance to get these prices?
No. Every price and coupon shown is a cash-pay price that anyone can use without insurance. Compare the cash price against your insurance copay and use whichever is lower.