Savings guide
How to Save on Tylenol (Acetaminophen) 500 mg
Generic Acetaminophen averages $4.27 vs brand Tylenol at $14.99 — a 72% difference.
Current lowest price
The lowest cash price we track for Tylenol 500 mg is about $4.27. Prices update as pharmacies change them — see the full live table below.
Compare live Tylenol prices →Generic vs brand
The FDA requires generic medications to demonstrate bioequivalence, meaning the same active ingredient, strength, dosage form, and route of administration as the brand-name product. A generic version of Acetaminophen works the same way in the body as brand Tylenol.
Because generics don't carry the original research and marketing costs, they usually cost far less while meeting the same FDA quality, strength, and purity standards. Read our generic vs. brand explainer →
Cheapest pharmacies for Tylenol
Compare live prices on the Tylenol page to see the cheapest pharmacies near you.
Steps to save on Tylenol
1. Compare cash prices
Compare Tylenol cash prices across every US pharmacy before you fill — the same drug can cost several times more at one counter than another.
2. Check for a generic
Ask your prescriber or pharmacist about generic Acetaminophen, which is usually far cheaper than brand Tylenol and is FDA-rated therapeutically equivalent.
3. Apply a pharmacy coupon
Use a free discount coupon (such as GoodRx) at the pharmacy counter. Coupons and insurance cannot be combined, so compare the cash-coupon price against your copay.
4. Ask about patient assistance
Ask the manufacturer and nonprofit foundations whether a patient-assistance or copay program covers this medication if you qualify.
5. Try mail-order
Mail-order pharmacies like Mark Cuban Cost Plus often price 90-day generic supplies below retail. Confirm the drug is in their catalog first.
FAQ
How can I save money on Tylenol?
Compare cash prices across pharmacies, ask about generic Acetaminophen, use a free coupon, and check for a manufacturer assistance program. Prices for the same drug vary widely between pharmacies.
Is there a generic version of Tylenol?
Yes — Acetaminophen is available as a generic and is usually much cheaper than brand Tylenol. The FDA requires it to have the same active ingredient, strength, and dosage form.
Does Tylenol have a manufacturer savings program?
We don't have a verified manufacturer savings program on file for Tylenol. Compare pharmacy cash prices and coupons, which anyone can use without enrollment.
Which pharmacy has the cheapest Tylenol?
Cash prices change often. Compare the live price table on this drug's page — Mark Cuban Cost Plus and Costco are frequently cheapest for generics.
Do I need insurance to get these prices?
No. Every price and coupon shown is a cash-pay price that anyone can use without insurance. Compare the cash price against your insurance copay and use whichever is lower.