Savings guide
How to Save on Zestoretic (Hydrochlorothiazide/Lisinopril) 25/20 mg
Generic Hydrochlorothiazide/Lisinopril averages $1.27 vs brand Zestoretic at $375.70 — a 100% difference.
Current lowest price
The lowest cash price we track for Zestoretic 25/20 mg is about $0.79. Prices update as pharmacies change them — see the full live table below.
Compare live Zestoretic prices →Generic vs brand
The FDA requires generic medications to demonstrate bioequivalence, meaning the same active ingredient, strength, dosage form, and route of administration as the brand-name product. A generic version of Hydrochlorothiazide/Lisinopril works the same way in the body as brand Zestoretic.
Because generics don't carry the original research and marketing costs, they usually cost far less while meeting the same FDA quality, strength, and purity standards. Read our generic vs. brand explainer →
Cheapest pharmacies for Zestoretic
- Costco Pharmacy$0.79
- Publix Pharmacy$0.88
- Meijer Pharmacy$0.90
Steps to save on Zestoretic
1. Compare cash prices
Compare Zestoretic cash prices across every US pharmacy before you fill — the same drug can cost several times more at one counter than another.
2. Check for a generic
Ask your prescriber or pharmacist about generic Hydrochlorothiazide/Lisinopril, which is usually far cheaper than brand Zestoretic and is FDA-rated therapeutically equivalent.
3. Apply a pharmacy coupon
Use a free discount coupon (such as GoodRx) at the pharmacy counter. Coupons and insurance cannot be combined, so compare the cash-coupon price against your copay.
4. Ask about patient assistance
Ask the manufacturer and nonprofit foundations whether a patient-assistance or copay program covers this medication if you qualify.
5. Try mail-order
Mail-order pharmacies like Mark Cuban Cost Plus often price 90-day generic supplies below retail. Confirm the drug is in their catalog first.
FAQ
How can I save money on Zestoretic?
Compare cash prices across pharmacies, ask about generic Hydrochlorothiazide/Lisinopril, use a free coupon, and check for a manufacturer assistance program. Prices for the same drug vary widely between pharmacies.
Is there a generic version of Zestoretic?
Yes — Hydrochlorothiazide/Lisinopril is available as a generic and is usually much cheaper than brand Zestoretic. The FDA requires it to have the same active ingredient, strength, and dosage form.
Does Zestoretic have a manufacturer savings program?
We don't have a verified manufacturer savings program on file for Zestoretic. Compare pharmacy cash prices and coupons, which anyone can use without enrollment.
Which pharmacy has the cheapest Zestoretic?
Right now Costco Pharmacy shows one of the lowest cash prices, around $0.79. Mark Cuban Cost Plus and Costco are frequently the cheapest for generics.
Do I need insurance to get these prices?
No. Every price and coupon shown is a cash-pay price that anyone can use without insurance. Compare the cash price against your insurance copay and use whichever is lower.