Biologics Medications: Comparing Costs and Ways to Save

Biologics are complex medications made from living cells, and they are among the most expensive drugs on the market. Unlike small-molecule drugs, they don't have traditional generics; instead, lower-cost "biosimilars" may be available once a biologic loses exclusivity.

Because list prices are so high, most cost relief in this category comes from coverage and assistance rather than shopping cash prices. Biosimilars can cost less than the reference biologic, manufacturers run copay and patient-assistance programs for many branded biologics, and nonprofit foundations sometimes help with specific conditions. The medications below link to their own pages; whether a biosimilar or program applies to you is a clinical and eligibility question for your care team.

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Biologics medications (53)

Each medication links to its own page with live cash and discount prices. Prices vary by pharmacy, location, quantity, and eligibility.

Frequently asked questions

What is a biosimilar and can it save money?

A biosimilar is a medication that is highly similar to an already-approved biologic, with no clinically meaningful differences. Biosimilars can cost less than the original biologic. Whether one is appropriate for you is a decision for your prescriber. Our biosimilars guide explains the cost side.

Why are biologics so expensive?

Biologics are costly to develop and manufacture, and many face little or no lower-cost competition while under exclusivity. That keeps list prices high. Copay cards, patient-assistance programs, and biosimilars (when available) are the main ways patients reduce out-of-pocket cost.

Do manufacturer or nonprofit programs help with biologics?

Yes. Many biologic manufacturers offer copay assistance for commercially insured patients, and independent nonprofit foundations sometimes help with specific diagnoses. Eligibility varies and government-insurance patients are often excluded from manufacturer copay cards. See our copay card and patient-assistance guides.

Related savings guides

Biosimilars: The Generic-Style Savings for Biologic Drugs
Biosimilars offer generic-style savings for expensive biologic drugs. Learn how they're approved, how they differ from generics, and what they can save you.
How Manufacturer Copay Cards Work (and Their Limits)
Manufacturer copay cards can lower what you pay for a brand-name drug, but they have real limits. Learn who can use them and where they fall short.
Patient Assistance Programs: Who Qualifies and How to Apply
How manufacturer and nonprofit patient assistance programs work, who typically qualifies by income, and what documents you need to apply.

This page is for cost and savings education only. It is not medical advice and makes no claims about which medication is right for you or how well any drug works. Talk to your doctor or pharmacist about your specific medications and coverage. Prices vary by pharmacy, location, quantity, and eligibility.

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Biologics Medications: Comparing Costs and Ways to Save

Biologics medications (53)

Frequently asked questions

Related savings guides

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