Semaglutide vs tirzepatide
As of August 2026, Compounded semaglutide starts at $149 and Compounded tirzepatide starts at $299 through BetterBuyRx online care. Two GLP-1 class weight loss programs with published monthly pricing, compared on price, format, and FDA label facts for the underlying molecules.
This page does not rank the two options. It lays out published prices and sourced label facts side by side; a licensed provider reviews your health history and decides what fits your case, if anything.
Provider approval required. A licensed provider reviews every request and prescribes only when clinically appropriate, we never sell prescription medication directly.
Compounded medications are not FDA-approved
Compounded medications, including compounded semaglutide and compounded tirzepatide, are not FDA-approved as compounded products. The FDA does not review compounded drugs for safety, effectiveness, or quality before they are marketed. A licensed provider will determine whether a compounded or brand-name medication is appropriate for you.
Side by side
Catalog facts, side by side
Every fact in this table comes from the live catalog; every price comes from the care price engine.
| Fact | Compounded semaglutide | Compounded tirzepatide |
|---|---|---|
| Published price from | $149 | $299 |
| Program options | 4 | 4 |
| Dose or format | 0.5 mg / week, 0.75 mg / week, 1 mg+ / week, Daily oral | 5 mg / week, 7.5 mg / week, 10 mg+ / week, Daily oral |
| Billing | monthly | monthly |
Compounded semaglutide: Weekly injection tiers from 0.5 mg up, plus a daily oral option, all at one flat monthly price.
Compounded tirzepatide: Weekly injection tiers from 5 mg up, plus a daily oral option; the catalog describes the starting tier as a dual-agonist dose.
Published pricing
Every option, one published price
Every treatment has one published price, and the price you see is the price you are charged at booking.
Compounded semaglutide
| Treatment | Dose or format | Billing | Published price |
|---|---|---|---|
| Semaglutide · 0.5 mg | 0.5 mg / week | monthly | $149/mo |
| Semaglutide · 0.75 mg | 0.75 mg / week | monthly | $149/mo |
| Semaglutide · 1 mg+ | 1 mg+ / week | monthly | $149/mo |
| Oral semaglutide | Daily oral | monthly | $149/mo |
Compounded tirzepatide
| Treatment | Dose or format | Billing | Published price |
|---|---|---|---|
| Tirzepatide · 5 mg | 5 mg / week | monthly | $299/mo |
| Tirzepatide · 7.5 mg | 7.5 mg / week | monthly | $299/mo |
| Tirzepatide · 10 mg+ | 10 mg+ / week | monthly | $299/mo |
| Oral tirzepatide | Daily oral | monthly | $299/mo |
From the FDA labels
What the FDA labels say
The excerpts below come from the FDA-approved labels for the branded semaglutide and tirzepatide products. The programs dispense compounded preparations, which are not the branded products and are not FDA-approved.
Compounded semaglutide
INDICATIONS AND USAGE OZEMPIC is indicated: • as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. • to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction or non-fatal stroke) in adults with type 2 diabetes mellitus and established cardiovascular disease. • to reduce the risk of sustained eGFR decline, end-stage kidney disease, and cardiovascular death in adults with type 2 diabetes mellitus and chronic kidney disease. [...]
Boxed warning: WARNING: RISK OF THYROID C-CELL TUMORS • In rodents, semaglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. [...] WARNINGS AND PRECAUTIONS • Acute Pancreatitis: Has been observed in patients treated with GLP-1 receptor agonists, including OZEMPIC. Discontinue if pancreatitis is suspected. ( 5.2 ) • Diabetic Retinopathy Complications: Has been reported in a clinical trial. Patients with a history of diabetic retinopathy should be monitored. ( 5.3 ) • Never share an OZEMPIC pen between patients , even if the needle is changed. [...]
Source: FDA label for Ozempic via DailyMed · openFDA, accessed 2026-08-31.
Compounded tirzepatide
INDICATIONS AND USAGE MOUNJARO ® is indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus. MOUNJARO ® is a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus. ( 1 )
Boxed warning: WARNING: RISK OF THYROID C-CELL TUMORS In both male and female rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. [...] WARNINGS AND PRECAUTIONS Acute Pancreatitis: Has been observed in patients treated with GLP-1 receptor agonists, or MOUNJARO. Discontinue if pancreatitis is suspected. ( 5.2 ) Hypoglycemia with Concomitant Use of Insulin Secretagogues or Insulin: Concomitant use with an insulin secretagogue or insulin may increase the risk of hypoglycemia, including severe hypoglycemia. Reducing dose of insulin secretagogue or insulin may be necessary. [...]
Source: FDA label for MOUNJARO via DailyMed · openFDA, accessed 2026-08-31.
Go deeper
Full guides for each option
Each treatment page carries the full price table, label excerpts with sources, and answers.
- Compounded semaglutide guide with published pricing and sourced label sections.
- Compounded tirzepatide guide with published pricing and sourced label sections.
- All Weight loss options live on the Weight loss category page.
Questions
Semaglutide vs tirzepatide, answered
What do Compounded semaglutide and Compounded tirzepatide cost at BetterBuyRx?
How do I choose between Compounded semaglutide and Compounded tirzepatide?
Are the compounded preparations the same as branded products?
Start with the Weight loss program
The program page covers the online visit, the provider review, and exactly what the published price includes. A free call with the care team is available before you book anything.
Go to the Weight loss program