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How much does Prednisone 5 mg cost without insurance?

As of July 2026, the lowest verified cash price for Prednisone 5 mg (Prednisone) is $4.00 at H-E-B Pharmacy, based on 24 verified US pharmacy quotes. You don't need insurance to fill it — every price below is a real quote we verified, not an estimate or an insurance copay.

Pharmacy / sourceTypeVerified cash price
H-E-B Pharmacyprogram$4.00
Costco Pharmacypharmacy$4.00
Mark Cuban Cost Pluspharmacy$5.69
Mark Cuban Cost Pluspharmacy$6.38
Mark Cuban Cost Pluspharmacy$7.07
BetterBuy Rxcoupon$7.19

Last verified Jul 19, 2026. Cash prices only, from verified public retail and mail-order sources — no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.

Common questions

What is the cheapest way to buy Prednisone 5 mg without insurance?
The lowest verified cash price we currently have for Prednisone 5 mg (Prednisone) is $4.00 at H-E-B Pharmacy, from 24 verified pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
Is a generic version of Prednisone available?
Prednisone is dispensed as Prednisone. Cash prices above reflect what US pharmacies verified most recently.

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