NyQuil
Generic Acetaminophen/Dextromethorphan/Doxylamine · liquid · Rx required · Nighttime cold & flu relief.
Fetching live prices…
Local BetterBuy Rx prices near you
Enter your ZIP to check real pharmacy prices in your area with the free BetterBuy Rx discount card. No ZIP? The national price is in the results above.
About NyQuil
NyQuil is a brand of Acetaminophen/Dextromethorphan/Doxylamine, a cough/cold medication supplied as liquid in a 325/15/6.25 mg strength. It is commonly used for nighttime cold & flu relief.
An FDA-approved generic (Acetaminophen/Dextromethorphan/Doxylamine) is available and typically costs less than the brand, compare both cash prices in the results above before you fill.
Ways to save on NyQuil
Choosing the generic (Acetaminophen/Dextromethorphan/Doxylamine) instead of the brand can lower your cost, on average about $8.00 per fill (57% off the brand price) in our catalog, though the exact price varies by pharmacy, location, quantity, and eligibility. Compare the live cash and discount prices above, and ask about a 90-day supply if you take it long-term.
Don't pay for the NyQuil Cold & Flu Nighttime label
Active ingredient: Acetaminophen 325mg, Dextromethorphan HBr 15mg, Doxylamine succinate 6.25mg per 15mL
- ✓CVS Health Nighttime Cold & Flu
- ✓Walgreens Wal-Som Nighttime
- ✓Equate Nighttime Cold & Flu
- ✓Up&Up Nighttime Cold & Flu
- ✓Amazon Basic Care Nighttime Cold & Flu
Active ingredients are taken from the FDA Drug Facts panel (DailyMed). Store-brand prices are typical US shelf estimates and vary by location. Ask the pharmacist if you can't spot the store-brand version.
Related savings guides
Frequently asked questions
Is generic Acetaminophen/Dextromethorphan/Doxylamine the same as NyQuil?
Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.
How much can I save by choosing the generic?
On average $8.00 per fill (57% off the brand price). Savings vary by pharmacy, see live prices above.
Do I need insurance to get this price?
No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.
How often is this price updated?
At minimum every 72 hours. Many sources refresh every few hours.
Related medications
Compare NyQuil with other options and see the generic price.
Cheapest NyQuil alternatives
Compare NyQuil with…
Important safety information
Information for general comparison only. Not medical advice. Confirm with your pharmacist.