Apixaban
Sold as Eliquis
Apixaban is a direct oral anticoagulant (DOAC) used to prevent stroke in atrial fibrillation and to treat or prevent venous thromboembolism.
As of August 2026, Apixaban (5 mg) cash prices on BetterBuyRx start at $90.00 across 4 verified sources (lowest at RxConnected.com). The free BetterBuyRx discount card is compared live on the drug page when a partner network prices this combo. Prices change; confirm at the counter.
What it treats
Stroke prevention in non-valvular atrial fibrillation, treatment and prevention of DVT/PE, post-orthopedic surgery prophylaxis.
Typical dosing
Typical adult dose: 5 mg twice daily (2.5 mg in select patients).
Side effects
Bleeding (most important), bruising, anemia.
Interactions to know
Avoid combining with other anticoagulants/antiplatelets unless prescribed. Strong CYP3A4/P-gp inhibitors and inducers affect levels.
Pregnancy & breastfeeding
Generally avoided.
Live price snapshot
| Source | Type | Cash price |
|---|---|---|
| RxConnected.com | pharmacy | $90.00 |
| PlanetDrugsDirect | pharmacy | $92.99 |
| Costco Pharmacy | pharmacy | $1349.00 |
| Mark Cuban Cost Plus | pharmacy | $23810.00 |
Save with the free BetterBuyRx card
The BetterBuyRx discount card is free, no signup, no insurance needed. When a partner network prices Apixaban, the card price appears live on the drug page with its BIN, PCN, Group, and Member ID. Show the card at the pharmacy counter; it can't be combined with insurance.
Frequently asked questions
- How much does Apixaban cost without insurance?
- As of the latest check, the lowest verified cash price we've found for Apixaban is $90.00 at RxConnected.com, across 4 verified sources. Cash prices are unregulated and vary by pharmacy, so compare before you fill and confirm the price at the counter.
- Can I use the free BetterBuyRx discount card for Apixaban?
- Yes. The free BetterBuyRx discount card is compared live on the drug page and, when a partner network prices Apixaban, shows the card price with its BIN, PCN, Group, and Member ID. It can't be combined with insurance.
- Why does the price of Apixaban vary so much between pharmacies?
- U.S. cash prescription prices are unregulated, each pharmacy sets its own markup, and discount programs and mail-order sources widen the spread further (this is common across the Direct oral anticoagulant (factor Xa inhibitor) class). That's why comparing verified prices before you fill can save money.
Clinical content reviewed by the BetterBuyRx clinical team.
Educational only. Not medical advice. Always confirm with your prescriber or pharmacist.