How much does Apraclonidine cost without insurance?

As of the latest check, the lowest verified cash price we've found for Apraclonidine is $17.40 at BetterBuy Rx, across 1 verified source. Cash prices are unregulated and vary by pharmacy, so compare before you fill and confirm the price at the counter.

Is there a generic for Apraclonidine?

Yes. Apraclonidine is the generic; it is also sold under brand names such as Iopidine. The generic is typically far cheaper than brand and is what our verified cash prices reflect.

Can I use the free BetterBuyRx discount card for Apraclonidine?

Yes. The free BetterBuyRx discount card is compared live on the drug page and, when a partner network prices Apraclonidine, shows the card price with its BIN, PCN, Group, and Member ID. It can't be combined with insurance.

Why does the price of Apraclonidine vary so much between pharmacies?

U.S. cash prescription prices are unregulated, each pharmacy sets its own markup, and discount programs and mail-order sources widen the spread further (this is common across the Eye Drops class). That's why comparing verified prices before you fill can save money.

Eye DropsGeneric available

Apraclonidine

Sold as Iopidine

Apraclonidine (sold as Iopidine) is used for: Ophthalmic condition treatment.

Compare prices →~$0.00 / mo (generic, NADAC)

As of August 2026, Apraclonidine (0.5%) cash prices on BetterBuyRx start at $17.40 across 1 verified source (lowest at BetterBuy Rx). The free BetterBuyRx discount card is compared live on the drug page when a partner network prices this combo. Prices change; confirm at the counter.

Live price snapshot

Source	Type	Cash price
BetterBuy Rx	coupon	$17.40

See all prices for Apraclonidine →Prices checked Aug 23, 2026

Save with the free BetterBuyRx card

The BetterBuyRx discount card is free, no signup, no insurance needed. When a partner network prices Apraclonidine, the card price appears live on the drug page with its BIN, PCN, Group, and Member ID. Show the card at the pharmacy counter; it can't be combined with insurance.

Get the free card →Apraclonidine coupon & card price →

Frequently asked questions

How much does Apraclonidine cost without insurance?: As of the latest check, the lowest verified cash price we've found for Apraclonidine is $17.40 at BetterBuy Rx, across 1 verified source. Cash prices are unregulated and vary by pharmacy, so compare before you fill and confirm the price at the counter.
Is there a generic for Apraclonidine?: Yes. Apraclonidine is the generic; it is also sold under brand names such as Iopidine. The generic is typically far cheaper than brand and is what our verified cash prices reflect.
Can I use the free BetterBuyRx discount card for Apraclonidine?: Yes. The free BetterBuyRx discount card is compared live on the drug page and, when a partner network prices Apraclonidine, shows the card price with its BIN, PCN, Group, and Member ID. It can't be combined with insurance.
Why does the price of Apraclonidine vary so much between pharmacies?: U.S. cash prescription prices are unregulated, each pharmacy sets its own markup, and discount programs and mail-order sources widen the spread further (this is common across the Eye Drops class). That's why comparing verified prices before you fill can save money.

We're still expanding this entry. For full prescribing information, see the FDA label below.

Clinical content reviewed by the BetterBuyRx clinical team.

Educational only. Not medical advice. Always confirm with your prescriber or pharmacist.