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Cardiovascular

Isosorbide Mononitrate

Sold as Isosorbide Mononitrate

Isosorbide Mononitrate (sold as Isosorbide Mononitrate) is used for: Long-acting nitrate for angina prevention. Isosorbide comes in two salts: mononitrate (ISMN, once or twice daily) and dinitrate (ISDN, three times daily). This page covers mononitrate.

Compare prices →~$0.00 / mo (generic, NADAC)

As of August 2026, Isosorbide Mononitrate (20 mg) cash prices on BetterBuyRx start at $6.12 across 5 verified sources (lowest at Blink Health). The free BetterBuyRx discount card recently showed $18.38 in the 100xx ZIP area (checked Aug 24, 2026); card prices vary by ZIP, so enter yours on the drug page for local pharmacy prices. Prices change; confirm at the counter.

Live price snapshot

SourceTypeCash price
Blink Healthpharmacy$6.12
Mark Cuban Cost Pluspharmacy$8.45
Honeybee Healthpharmacy$17.00
BetterBuy Rxcoupon$18.38
Mark Cuban Cost Pluspharmacy$162.70

Save with the free BetterBuyRx card

The BetterBuyRx discount card is free, no signup, no insurance needed. It recently showed $18.38 for Isosorbide Mononitrate at a partner-network pharmacy in the 100xx ZIP area, card prices vary by ZIP, so enter yours on the drug page for local pharmacy prices. Show the card at the pharmacy counter; it can't be combined with insurance.

Frequently asked questions

How much does Isosorbide Mononitrate cost without insurance?
As of the latest check, the lowest verified cash price we've found for Isosorbide Mononitrate is $6.12 at Blink Health, across 5 verified sources. Cash prices are unregulated and vary by pharmacy, so compare before you fill and confirm the price at the counter.
Can I use the free BetterBuyRx discount card for Isosorbide Mononitrate?
Yes. The free BetterBuyRx discount card recently showed $18.38 for this medication at a partner-network pharmacy in the 100xx ZIP area (checked Aug 24, 2026). Card prices vary by ZIP, enter yours on the drug page to see local pharmacy prices. Show the card (BIN, PCN, Group, and Member ID where required) at the counter; it can't be combined with insurance.
Why does the price of Isosorbide Mononitrate vary so much between pharmacies?
U.S. cash prescription prices are unregulated, each pharmacy sets its own markup, and discount programs and mail-order sources widen the spread further (this is common across the Cardiovascular class). That's why comparing verified prices before you fill can save money.

We're still expanding this entry. For full prescribing information, see the FDA label below.

Clinical content reviewed by the BetterBuyRx clinical team.

Educational only. Not medical advice. Always confirm with your prescriber or pharmacist.