Lamotrigine
Sold as Lamictal
Lamotrigine (sold as Lamictal) is used for: Bipolar maintenance, epilepsy.
As of August 2026, Lamotrigine (100 mg) cash prices are compared live across verified pharmacies and mail-order pharmacies on BetterBuyRx, see the current numbers on the drug page below. Prices change; confirm at the counter.
Save with the free BetterBuyRx card
The BetterBuyRx discount card is free, no signup, no insurance needed. When a partner network prices Lamotrigine, the card price appears live on the drug page with its BIN, PCN, Group, and Member ID. Show the card at the pharmacy counter; it can't be combined with insurance.
Frequently asked questions
- How much does Lamotrigine cost without insurance?
- We compare cash prices for Lamotrigine live across verified pharmacies on the drug page, the current lowest price is shown there. Cash prices are unregulated and vary by pharmacy, so compare before you fill and confirm the price at the counter.
- Is there a generic for Lamotrigine?
- Yes. Lamotrigine is the generic; it is also sold under brand names such as Lamictal. The generic is typically far cheaper than brand and is what our verified cash prices reflect.
- Can I use the free BetterBuyRx discount card for Lamotrigine?
- Yes. The free BetterBuyRx discount card is compared live on the drug page and, when a partner network prices Lamotrigine, shows the card price with its BIN, PCN, Group, and Member ID. It can't be combined with insurance.
- Why does the price of Lamotrigine vary so much between pharmacies?
- U.S. cash prescription prices are unregulated, each pharmacy sets its own markup, and discount programs and mail-order sources widen the spread further (this is common across the Mental Health class). That's why comparing verified prices before you fill can save money.
Important safety information
Boxed warning, serious skin reactions (SJS/TEN)
BOXED WARNING: Lamotrigine (Lamictal) can cause serious, sometimes fatal skin rashes, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). The risk is highest in the first 2-8 weeks of treatment and increases significantly with faster-than- recommended dose increases, the starting dose and titration schedule below must never be exceeded. Stop lamotrigine immediately and seek emergency care at the first sign of rash, fever, swollen lymph nodes, or mouth/eye sores, unless your prescriber has told you the rash is clearly unrelated to the drug.
Mandatory slow-titration schedule (adult monotherapy, not taking valproate)
- Weeks 1-2: 25 mg once daily
- Weeks 3-4: 50 mg once daily
- Week 5 onward: increase by 25-50 mg/day every 1-2 weeks, per prescriber guidance, toward maintenance
If you take valproate (Depakote) or have missed doses for more than a few days, your titration schedule is different and slower, follow your prescriber's specific instructions, never a generic schedule.
Antiepileptic drug safety warning
Antiepileptic drugs (AEDs), including this medication, increase the risk of suicidal thoughts or behavior in patients taking them for any indication, not just epilepsy. Anyone starting or already taking an AED should be monitored for new or worsening depression, suicidal thoughts or behavior, or any unusual changes in mood. Contact your prescriber right away, or call or text 988 (Suicide & Crisis Lifeline), if these occur. Do not stop an AED abruptly without medical guidance, sudden discontinuation can trigger withdrawal seizures.
We're still expanding this entry. For full prescribing information, see the FDA label below.
Clinical content reviewed by the BetterBuyRx clinical team.
Educational only. Not medical advice. Always confirm with your prescriber or pharmacist.