How much does Nalmefene cost without insurance?

We compare cash prices for Nalmefene live across verified pharmacies on the drug page, the current lowest price is shown there. Cash prices are unregulated and vary by pharmacy, so compare before you fill and confirm the price at the counter.

Is there a generic for Nalmefene?

Yes. Nalmefene is the generic; it is also sold under brand names such as Opvee. The generic is typically far cheaper than brand and is what our verified cash prices reflect.

Can I use the free BetterBuyRx discount card for Nalmefene?

Yes. The free BetterBuyRx discount card is compared live on the drug page and, when a partner network prices Nalmefene, shows the card price with its BIN, PCN, Group, and Member ID. It can't be combined with insurance.

Why does the price of Nalmefene vary so much between pharmacies?

U.S. cash prescription prices are unregulated, each pharmacy sets its own markup, and discount programs and mail-order sources widen the spread further (this is common across the Substance Use class). That's why comparing verified prices before you fill can save money.

Substance UseGeneric available

Nalmefene

Sold as Opvee

Nalmefene (sold as Opvee) is used for: Substance-use disorder treatment.

Compare prices →~$0.00 / mo (generic, NADAC)

As of August 2026, Nalmefene (2.7mg) cash prices are compared live across verified pharmacies and mail-order pharmacies on BetterBuyRx, see the current numbers on the drug page below. Prices change; confirm at the counter.

Save with the free BetterBuyRx card

The BetterBuyRx discount card is free, no signup, no insurance needed. When a partner network prices Nalmefene, the card price appears live on the drug page with its BIN, PCN, Group, and Member ID. Show the card at the pharmacy counter; it can't be combined with insurance.

Get the free card →Nalmefene coupon & card price →

Frequently asked questions

How much does Nalmefene cost without insurance?: We compare cash prices for Nalmefene live across verified pharmacies on the drug page, the current lowest price is shown there. Cash prices are unregulated and vary by pharmacy, so compare before you fill and confirm the price at the counter.
Is there a generic for Nalmefene?: Yes. Nalmefene is the generic; it is also sold under brand names such as Opvee. The generic is typically far cheaper than brand and is what our verified cash prices reflect.
Can I use the free BetterBuyRx discount card for Nalmefene?: Yes. The free BetterBuyRx discount card is compared live on the drug page and, when a partner network prices Nalmefene, shows the card price with its BIN, PCN, Group, and Member ID. It can't be combined with insurance.
Why does the price of Nalmefene vary so much between pharmacies?: U.S. cash prescription prices are unregulated, each pharmacy sets its own markup, and discount programs and mail-order sources widen the spread further (this is common across the Substance Use class). That's why comparing verified prices before you fill can save money.

We're still expanding this entry. For full prescribing information, see the FDA label below.

Clinical content reviewed by the BetterBuyRx clinical team.

Educational only. Not medical advice. Always confirm with your prescriber or pharmacist.