Tadalafil
Sold as Cialis, Adcirca
Tadalafil is a long-acting PDE5 inhibitor for erectile dysfunction, BPH, and pulmonary arterial hypertension.
As of August 2026, Tadalafil (20 mg) cash prices on BetterBuyRx start at $6.69 across 5 verified sources (lowest at Mark Cuban Cost Plus). The free BetterBuyRx discount card recently showed $33.25 in the 960xx ZIP area (checked Aug 22, 2026); card prices vary by ZIP, so enter yours on the drug page for local pharmacy prices. Prices change; confirm at the counter.
What it treats
Erectile dysfunction, BPH, pulmonary arterial hypertension.
Typical dosing
ED: 10-20 mg as needed before activity, or 2.5-5 mg daily.
Side effects
Headache, flushing, indigestion, back pain, nasal congestion.
Interactions to know
Do NOT combine with nitrates, dangerous drop in blood pressure. Caution with alpha-blockers.
Pregnancy & breastfeeding
Not applicable for ED indication; PAH use is specialized.
Live price snapshot
| Source | Type | Cash price |
|---|---|---|
| Mark Cuban Cost Plus | pharmacy | $6.69 |
| Costco Pharmacy | pharmacy | $12.99 |
| PlanetDrugsDirect | pharmacy | $48.99 |
| Honeybee Health | pharmacy | $51.00 |
| Blink Health | pharmacy | $90.90 |
Save with the free BetterBuyRx card
The BetterBuyRx discount card is free, no signup, no insurance needed. It recently showed $33.25 for Tadalafil at a partner-network pharmacy in the 960xx ZIP area, card prices vary by ZIP, so enter yours on the drug page for local pharmacy prices. Show the card at the pharmacy counter; it can't be combined with insurance.
Frequently asked questions
- How much does Tadalafil cost without insurance?
- As of the latest check, the lowest verified cash price we've found for Tadalafil is $6.69 at Mark Cuban Cost Plus, across 5 verified sources. Cash prices are unregulated and vary by pharmacy, so compare before you fill and confirm the price at the counter.
- Is there a generic for Tadalafil?
- Yes. Tadalafil is the generic; it is also sold under brand names such as Cialis, Adcirca. The generic is typically far cheaper than brand and is what our verified cash prices reflect.
- Can I use the free BetterBuyRx discount card for Tadalafil?
- Yes. The free BetterBuyRx discount card recently showed $33.25 for this medication at a partner-network pharmacy in the 960xx ZIP area (checked Aug 22, 2026). Card prices vary by ZIP, enter yours on the drug page to see local pharmacy prices. Show the card (BIN, PCN, Group, and Member ID where required) at the counter; it can't be combined with insurance.
- Why does the price of Tadalafil vary so much between pharmacies?
- U.S. cash prescription prices are unregulated, each pharmacy sets its own markup, and discount programs and mail-order sources widen the spread further (this is common across the PDE5 inhibitor class). That's why comparing verified prices before you fill can save money.
Clinical content reviewed by the BetterBuyRx clinical team.
Educational only. Not medical advice. Always confirm with your prescriber or pharmacist.