How much does Prilosec OTC 20 mg cost without insurance?
As of July 2026, the lowest verified cash price for Prilosec OTC 20 mg (Omeprazole) is $4.50 at Costco Pharmacy, based on 46 verified US pharmacy quotes. You don't need insurance to fill it — every price below is a real quote we verified, not an estimate or an insurance copay.
| Pharmacy / source | Type | Verified cash price |
|---|---|---|
| Costco Pharmacy | pharmacy | $4.50 |
| Costco Pharmacy | pharmacy | $4.50 |
| Blink Health | pharmacy | $5.00 |
| Amazon Pharmacy RxPass | program | $5.00 |
| Amazon Pharmacy RxPass | program | $5.00 |
| Amazon Pharmacy RxPass | program | $5.00 |
Last verified Jul 21, 2026. Cash prices only, from verified public retail and mail-order sources — no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.
Common questions
- What is the cheapest way to buy Prilosec OTC 20 mg without insurance?
- The lowest verified cash price we currently have for Prilosec OTC 20 mg (Omeprazole) is $4.50 at Costco Pharmacy, from 46 verified pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
- Is a generic version of Prilosec OTC available?
- Prilosec OTC is dispensed as Omeprazole. Cash prices above reflect what US pharmacies verified most recently.