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How much does Valtrex 500 mg cost without insurance?

As of August 2026, the lowest verified cash price for Valtrex 500 mg (Valacyclovir) is $10.52 at Mark Cuban Cost Plus, based on 6 verified US pharmacy quotes. You don't need insurance to fill it, every price below is a real quote we verified, not an estimate or an insurance copay.

BetterBuyRx card price in the 750xx ZIP area: $15.48 (checked Aug 27, 2026). Card prices vary by ZIP, enter yours on the drug page for local pharmacy prices. We show home delivery too and always surface it first when it is cheaper.

Pharmacy / sourceTypeVerified cash price
Mark Cuban Cost Pluspharmacy$10.52
Blink Healthpharmacy$14.60
HealthWarehousepharmacy$19.50
Honeybee Healthpharmacy$24.10
PlanetDrugsDirectpharmacy$65.99
RxConnected.compharmacy$114.00

Last verified Aug 23, 2026. Cash prices only, from verified public retail and mail-order sources, no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.

Common questions

What is the cheapest way to buy Valtrex 500 mg without insurance?
The lowest verified cash price we currently have for Valtrex 500 mg (Valacyclovir) is $10.52 at Mark Cuban Cost Plus, from 6 verified pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
Is the BetterBuyRx card or home delivery cheaper for Valacyclovir?
Home delivery/retail is cheaper here: the lowest verified quote is $10.52 versus $15.48 on the BetterBuyRx card in the 750xx ZIP area for Valtrex 500 mg. Card prices vary by ZIP, enter yours on the drug page for local pharmacy prices. We show the delivery option first because it is the lower price.
Is a generic version of Valtrex available?
Yes: Valacyclovir is the generic of Valtrex and is what drives the low cash prices above.

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