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How much does Zyloprim 300 mg cost without insurance?

As of July 2026, the lowest verified cash price for Zyloprim 300 mg (Allopurinol) is $4.00 at H-E-B Pharmacy, based on 40 verified US pharmacy quotes. You don't need insurance to fill it — every price below is a real quote we verified, not an estimate or an insurance copay.

Pharmacy / sourceTypeVerified cash price
H-E-B Pharmacyprogram$4.00
Costco Pharmacypharmacy$4.50
Amazon Pharmacy RxPassprogram$5.00
Amazon Pharmacy RxPassprogram$5.00
Amazon Pharmacy RxPassprogram$5.00
Amazon Pharmacy RxPassprogram$5.00

Last verified Jul 19, 2026. Cash prices only, from verified public retail and mail-order sources — no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.

Common questions

What is the cheapest way to buy Zyloprim 300 mg without insurance?
The lowest verified cash price we currently have for Zyloprim 300 mg (Allopurinol) is $4.00 at H-E-B Pharmacy, from 40 verified pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
Is a generic version of Zyloprim available?
Yes — Allopurinol is the generic of Zyloprim and is what drives the low cash prices above.

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