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How much does Zyloprim 300 mg cost without insurance?

As of September 2026, the lowest verified cash price for Zyloprim 300 mg (Allopurinol) is $4.00 at H-E-B Pharmacy, based on 9 verified US pharmacy quotes. You don't need insurance to fill it, every price below is a real quote we verified, not an estimate or an insurance copay.

BetterBuyRx card price in the 286xx ZIP area: $7.08 (checked Sep 3, 2026). Card prices vary by ZIP, enter yours on the drug page for local pharmacy prices. We show home delivery too and always surface it first when it is cheaper.

Pharmacy / sourceTypeVerified cash price
H-E-B Pharmacyprogram$4.00
Costco Pharmacypharmacy$4.50
Amazon Pharmacy RxPassprogram$5.00
Mark Cuban Cost Pluspharmacy$5.93
Blink Healthpharmacy$7.80
BetterBuy Rxcoupon$8.34

Last verified Sep 3, 2026. Cash prices only, from verified public retail and mail-order sources, no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.

Common questions

What is the cheapest way to buy Zyloprim 300 mg without insurance?
The lowest verified cash price we currently have for Zyloprim 300 mg (Allopurinol) is $4.00 at H-E-B Pharmacy, from 9 verified pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
Is the BetterBuyRx card or home delivery cheaper for Allopurinol?
Home delivery/retail is cheaper here: the lowest verified quote is $4.00 versus $7.08 on the BetterBuyRx card in the 286xx ZIP area for Zyloprim 300 mg. Card prices vary by ZIP, enter yours on the drug page for local pharmacy prices. We show the delivery option first because it is the lower price.
Is a generic version of Zyloprim available?
Yes: Allopurinol is the generic of Zyloprim and is what drives the low cash prices above.

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