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What is the generic of Zyloprim?

The generic of Zyloprim is Allopurinol. As of July 2026, the lowest verified cash price for Allopurinol 300 mg is $4.00 at H-E-B Pharmacy, based on 40 verified US pharmacy quotes — every price below is a real quote we verified, not an estimate.

Pharmacy / sourceTypeVerified cash price
H-E-B Pharmacyprogram$4.00
Costco Pharmacypharmacy$4.50
Amazon Pharmacy RxPassprogram$5.00
Amazon Pharmacy RxPassprogram$5.00
Amazon Pharmacy RxPassprogram$5.00
Amazon Pharmacy RxPassprogram$5.00

Last verified Jul 19, 2026. Cash prices only, from verified public retail and mail-order sources — no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.

Common questions

What is the generic of Zyloprim?
The generic of Zyloprim is Allopurinol. It contains the same active ingredient and is the version that drives the low cash prices below.
How much does generic Zyloprim (Allopurinol) cost without insurance?
The lowest verified cash price we currently have for Allopurinol 300 mg is $4.00 at H-E-B Pharmacy, from 40 verified US pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
Is generic Allopurinol as effective as Zyloprim?
Generic Allopurinol must meet the same FDA standards for active ingredient, strength, and quality as Zyloprim. Ask your pharmacist if you have questions about switching.

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