What is the generic of Zyloprim?
The generic of Zyloprim is Allopurinol. As of September 2026, the lowest verified cash price for Allopurinol 300 mg is $4.00 at H-E-B Pharmacy, based on 9 verified US pharmacy quotes, every price below is a real quote we verified, not an estimate.
BetterBuyRx card price in the 286xx ZIP area: $7.08 (checked Sep 3, 2026). Card prices vary by ZIP, enter yours on the drug page for local pharmacy prices. We show home delivery too and always surface it first when it is cheaper.
| Pharmacy / source | Type | Verified cash price |
|---|---|---|
| H-E-B Pharmacy | program | $4.00 |
| Costco Pharmacy | pharmacy | $4.50 |
| Amazon Pharmacy RxPass | program | $5.00 |
| Mark Cuban Cost Plus | pharmacy | $5.93 |
| Blink Health | pharmacy | $7.80 |
| BetterBuy Rx | coupon | $8.34 |
Last verified Sep 3, 2026. Cash prices only, from verified public retail and mail-order sources, no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.
Common questions
- What is the generic of Zyloprim?
- The generic of Zyloprim is Allopurinol. It contains the same active ingredient and is the version that drives the low cash prices below.
- How much does generic Zyloprim (Allopurinol) cost without insurance?
- The lowest verified cash price we currently have for Allopurinol 300 mg is $4.00 at H-E-B Pharmacy, from 9 verified US pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
- Is generic Allopurinol as effective as Zyloprim?
- Generic Allopurinol must meet the same FDA standards for active ingredient, strength, and quality as Zyloprim. Ask your pharmacist if you have questions about switching.