How much does Dupixent cost without insurance?

Dupixent (Dupilumab) 300 mg/2 mL averages $3798.00 cash with no FDA-approved generic available. Live prices on this page update at least every 72 hours.

What pharmacy has the cheapest Dupixent?

Mail-order pharmacies and the manufacturer savings card typically offer the lowest cash cost for Dupixent. Exact rankings update live above.

Which pharmacy has the cheapest Dupixent in 2026?

Costco Pharmacy currently has the lowest verified cash price for Dupixent (Dupilumab) at $2289.04. Cost Plus Drugs and Costco are consistently the cheapest US pharmacies for most generics.

Is CVS or Walgreens cheaper for Dupixent?

Neither — both are typically 30–60% more expensive than Cost Plus or Costco. CVS and Walgreens consistently rank as the most expensive cash-pay pharmacies for Dupilumab.

How often do these prices change?

BetterBuyRx refreshes prices at minimum every 72 hours from public retail price feeds. Mail-order partners like Cost Plus and Amazon Pharmacy can change daily.

Specialty

Dupixent

Name: Dupixent 300 mg/2 mL (Dupilumab)
Brand: Dupixent
SKU: dupixent
Availability: InStock

Active ingredient: Dupilumab · 300 mg/2 mL · pen · qty 2

No FDA-approved generic available — manufacturer savings card may cut cost 50%+

Atopic dermatitis, asthma.

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Common uses & information

Dupixent is a brand of Dupilumab, a specialty medication supplied as pen in a 300 mg/2 mL strength. It is commonly used for atopic dermatitis, asthma.

An FDA-approved generic (Dupilumab) is available and typically costs less than the brand — compare both cash prices in the table above before you fill.

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Want to dig deeper on Dupixent 300 mg/2 mL?

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Price summary

Form	Class	Brand avg	Generic avg	Savings
pen 300 mg/2 mL	Specialty	$3798.00	$3692.00	—

Clinical information

Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →

Manufacturer & patient assistance programs

For patient assistance, check NeedyMeds and RxAssist.

FAQ

Is there a generic for Dupixent?

Not yet. The FDA has not approved a generic equivalent for Dupixent (Dupilumab). A manufacturer savings card from the brand maker is usually the largest legitimate discount available today.

How much can I save by choosing the generic?

Currently no FDA-approved generic equivalent exists for Dupixent, so the brand and generic prices are similar.

Do I need insurance to get this price?

No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

Related medications

Compare Dupixent with other options and see the generic price.

See generic Dupilumab prices →

Cheapest Dupixent alternatives

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.