How much does Hydrea cost without insurance?

Generic Hydroxyurea 500 mg costs around $18.77 cash. Live prices on this page are verified within the last 72 hours.

What pharmacy has the cheapest Hydrea?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Hydroxyurea. CVS and Walgreens are the most expensive. Exact rankings update live above.

Blood disorders / oncology

Hydrea

Name: Hydrea 500 mg (Hydroxyurea)
Brand: Hydrea
SKU: hydroxyurea
Availability: InStock

Hydroxyurea · 500 mg · capsule · qty 30

Sickle cell disease (reduces painful crises), chronic myeloid leukemia, and other myeloproliferative disorders.

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Common uses & information

Hydrea is a brand of Hydroxyurea, a blood disorders / oncology medication supplied as capsule in a 500 mg strength. It is commonly used for sickle cell disease (reduces painful crises), chronic myeloid leukemia, and other myeloproliferative disorders.

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Price summary

Form	Class	Brand avg	Generic avg	Savings
capsule 500 mg	Rx	see live prices above	$18.77	—

Clinical information

Typical dosing

Dosing is weight-based and individualized by your prescriber, then adjusted based on regular blood counts. Never change your dose without medical guidance.

Side effects

Boxed warning: can cause severe bone marrow suppression (low blood cell counts), increasing infection and bleeding risk. Requires regular CBC (complete blood count) monitoring — typically every 2–4 weeks initially, then monthly once stable — to catch this early. Also associated with increased long-term skin cancer risk — use sun protection. Common: nausea, mouth sores, temporary hair thinning.

Interactions to know

Use with other bone-marrow-suppressing drugs or radiation can compound blood count drops. Live vaccines should generally be avoided during treatment — discuss with your prescriber.

Pregnancy & breastfeeding

Can cause fetal harm; not recommended during pregnancy. Effective contraception is advised during treatment for people who can become pregnant, and hydroxyurea should be stopped before planned pregnancy per your prescriber's guidance.

Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →

Manufacturer & patient assistance programs

For patient assistance, check NeedyMeds and RxAssist.

FAQ

Is generic Hydroxyurea the same as Hydrea?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

Currently no FDA-approved generic equivalent exists for Hydrea, so the brand and generic prices are similar.

Do I need insurance to get this price?

No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.