How much does Opvee cost without insurance?

Live cash prices for Opvee 2.7mg are verified within the last 72 hours — see the table above for the current cheapest source.

What pharmacy has the cheapest Opvee?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Nalmefene. CVS and Walgreens are the most expensive. Exact rankings update live above.

Which pharmacy has the cheapest Opvee in 2026?

Publix Pharmacy currently has the lowest verified cash price for Opvee (Nalmefene) at $0.00. Cost Plus Drugs and Costco are consistently the cheapest US pharmacies for most generics.

Is CVS or Walgreens cheaper for Opvee?

Neither — both are typically 30–60% more expensive than Cost Plus or Costco. CVS and Walgreens consistently rank as the most expensive cash-pay pharmacies for Nalmefene.

How often do these prices change?

BetterBuyRx refreshes prices at minimum every 72 hours from public retail price feeds. Mail-order partners like Cost Plus and Amazon Pharmacy can change daily.

Substance Use

Opvee

Name: Opvee 2.7mg (Nalmefene)
Brand: Opvee
SKU: opvee
Availability: InStock

Nalmefene · 2.7mg · spray · qty 2

Substance-use disorder treatment.

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Common uses & information

Opvee is a brand of Nalmefene, a substance use medication supplied as spray in a 2.7mg strength. It is commonly used for substance-use disorder treatment.

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Price summary

Form	Class	Brand avg	Generic avg	Savings
spray 2.7mg	Rx	$97.30	see live prices above	—

Clinical information

Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →

Manufacturer & patient assistance programs

For patient assistance, check NeedyMeds and RxAssist.

FAQ

Is generic Nalmefene the same as Opvee?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

Currently no FDA-approved generic equivalent exists for Opvee, so the brand and generic prices are similar.

Do I need insurance to get this price?

No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

Related medications

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.