How much does Premarin cost without insurance?

Premarin (Conjugated Estrogens) 0.625 mg costs around $212.00 cash for the generic and $289.00 for the brand. Live prices on this page are verified within the last 72 hours.

What pharmacy has the cheapest Premarin?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Conjugated Estrogens. CVS and Walgreens are the most expensive. Exact rankings update live above.

Which pharmacy has the cheapest Premarin in 2026?

Costco Pharmacy currently has the lowest verified cash price for Premarin (Conjugated Estrogens) at $131.44. Cost Plus Drugs and Costco are consistently the cheapest US pharmacies for most generics.

Is CVS or Walgreens cheaper for Premarin?

Neither — both are typically 30–60% more expensive than Cost Plus or Costco. CVS and Walgreens consistently rank as the most expensive cash-pay pharmacies for Conjugated Estrogens.

How often do these prices change?

BetterBuyRx refreshes prices at minimum every 72 hours from public retail price feeds. Mail-order partners like Cost Plus and Amazon Pharmacy can change daily.

Hormones

Premarin

Name: Premarin 0.625 mg (Conjugated Estrogens)
Brand: Premarin
SKU: premarin
Availability: InStock

Conjugated Estrogens · 0.625 mg · tablet · qty 30

Menopausal hormone therapy.

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Common uses & information

Premarin is a brand of Conjugated Estrogens, a hormones medication supplied as tablet in a 0.625 mg strength. It is commonly used for menopausal hormone therapy.

An FDA-approved generic (Conjugated Estrogens) is available and typically costs less than the brand — compare both cash prices in the table above before you fill.

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Price summary

Form	Class	Brand avg	Generic avg	Savings
tablet 0.625 mg	Rx	$289.00 — generic is cheaper, see recommendation	$212.00Generic recommended	27%

Clinical information

Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →

Manufacturer & patient assistance programs

For patient assistance, check NeedyMeds and RxAssist.

FAQ

Is generic Conjugated Estrogens the same as Premarin?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

On average $77.00 per fill (27% off the brand price). Savings vary by pharmacy — see live prices above.

Do I need insurance to get this price?

No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

Related medications

Compare Premarin with other options and see the generic price.

See generic Conjugated Estrogens prices →

See Estrace prices
Estradiol · 1 mg
from $18.40

Cheapest Premarin alternatives

Estrace — $18.40

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Premarin vs Estrace

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.