How much does Sinemet CR cost without insurance?

Sinemet CR (Carbidopa/Levodopa ER) 50 mg / 200 mg costs around $34.00 cash for the generic and $168.00 for the brand. Live prices on this page are verified within the last 72 hours.

What pharmacy has the cheapest Sinemet CR?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Carbidopa/Levodopa ER. CVS and Walgreens are the most expensive. Exact rankings update live above.

How much does Sinemet CR cost without insurance?

Sinemet CR (Carbidopa/Levodopa ER) 50 mg / 200 mg cash price averages $34.00 for the generic and $168.00 for the brand. Cost Plus and Costco usually have the lowest verified cash prices.

Is it cheaper to pay cash than use insurance for Sinemet CR?

For generics, the cash price (especially at Cost Plus, Amazon Pharmacy, Costco) is often lower than a typical insurance copay. You're allowed to skip insurance on any fill.

Can I buy Sinemet CR without a prescription?

No — Sinemet CR requires a prescription from a licensed prescriber. Telehealth services can issue one quickly when appropriate.

Neurology

Sinemet CR Carbidopa/Levodopa ER 50 mg / 200 mg

Name: Sinemet CR 50 mg / 200 mg (Carbidopa/Levodopa ER)
Brand: Sinemet CR
SKU: sinemet-cr
Availability: InStock

Carbidopa/Levodopa ER · 50 mg / 200 mg · tablet · qty 90

Also available in: 25/100 mg · 50/200 mg

Parkinson's disease — controlled-release dopamine replacement (also 25/100).

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Live verified prices

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Common uses & information

Sinemet CR is a brand of Carbidopa/Levodopa ER, a neurology medication supplied as tablet in a 50 mg / 200 mg strength. It is commonly used for parkinson's disease — controlled-release dopamine replacement (also 25/100).

An FDA-approved generic (Carbidopa/Levodopa ER) is available and typically costs less than the brand — compare both cash prices in the table above before you fill.

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Price summary

Form	Class	Brand avg	Generic avg	Savings
tablet 50 mg / 200 mg	Rx	$168.00 — generic is cheaper, see recommendation	$34.00Generic recommended	80%

Clinical information

Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →

Manufacturer & patient assistance programs

For patient assistance, check NeedyMeds and RxAssist.

FAQ

Is generic Carbidopa/Levodopa ER the same as Sinemet CR?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

On average $134.00 per fill (80% off the brand price). Savings vary by pharmacy — see live prices above.

Do I need insurance to get this price?

No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

Related medications

Compare Sinemet CR with other options and see the generic price.

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.