How much does Astagraf XL cost without insurance?

Live cash prices for Astagraf XL 0.5 mg are verified within the last 72 hours — see the table above for the current cheapest source.

What pharmacy has the cheapest Astagraf XL?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Tacrolimus (extended-release, once-daily). CVS and Walgreens are the most expensive. Exact rankings update live above.

Transplant

Astagraf XL Tacrolimus (extended-release, once-daily) 0.5 mg

Name: Astagraf XL 0.5 mg (Tacrolimus (extended-release, once-daily))
Brand: Astagraf XL
SKU: astagraf-xl-05mg
Availability: InStock

Tacrolimus (extended-release, once-daily) · 0.5 mg · extended-release capsule · qty 30

Prevents kidney transplant rejection — once-daily extended-release. Different mg dosing than immediate-release Prograf; conversion must be done by a transplant prescriber, never 1:1.

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Common uses & information

Astagraf XL is a brand of Tacrolimus (extended-release, once-daily), a transplant medication supplied as extended-release capsule in a 0.5 mg strength. It is commonly used for prevents kidney transplant rejection — once-daily extended-release. Different mg dosing than immediate-release Prograf; conversion must be done by a transplant prescriber, never 1:1.

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Price summary

Form	Class	Brand avg	Generic avg	Savings
extended-release capsule 0.5 mg	Rx	see live prices above	see live prices above	—

Clinical information

Narrow-therapeutic-index medication

This is a narrow-therapeutic-index medication. Do not switch between brand and generic manufacturers without close monitoring by your prescriber. Small differences in absorption can cause treatment failure or toxicity.

Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →

Manufacturer & patient assistance programs

For patient assistance, check NeedyMeds and RxAssist.

Other brands of Tacrolimus (extended-release, once-daily)

Same active ingredient, different brand. Compare prices.

FAQ

Is generic Tacrolimus (extended-release, once-daily) the same as Astagraf XL?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

Currently no FDA-approved generic equivalent exists for Astagraf XL, so the brand and generic prices are similar.

Do I need insurance to get this price?

No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.