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What is the generic of Tofranil?

The generic of Tofranil is Imipramine. As of July 2026, the lowest verified cash price for Imipramine 50mg is $7.48 at Mark Cuban Cost Plus, based on 9 verified US pharmacy quotes — every price below is a real quote we verified, not an estimate.

Pharmacy / sourceTypeVerified cash price
Mark Cuban Cost Pluspharmacy$7.48
Mark Cuban Cost Pluspharmacy$8.73
Honeybee Healthpharmacy$13.40
Honeybee Healthpharmacy$17.60
BetterBuy Rxcoupon$20.68
CanadaDrugsDirect.compharmacy$56.00

Last verified Jul 19, 2026. Cash prices only, from verified public retail and mail-order sources — no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.

Common questions

What is the generic of Tofranil?
The generic of Tofranil is Imipramine. It contains the same active ingredient and is the version that drives the low cash prices below.
How much does generic Tofranil (Imipramine) cost without insurance?
The lowest verified cash price we currently have for Imipramine 50mg is $7.48 at Mark Cuban Cost Plus, from 9 verified US pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
Is generic Imipramine as effective as Tofranil?
Generic Imipramine must meet the same FDA standards for active ingredient, strength, and quality as Tofranil. Ask your pharmacist if you have questions about switching.