How much does Prozac cost without insurance?

Prozac (Fluoxetine) 20 mg costs around $4.40 cash for the generic and $148.00 for the brand. Live prices on this page are verified within the last 72 hours.

What pharmacy has the cheapest Prozac?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Fluoxetine. CVS and Walgreens are the most expensive. Exact rankings update live above.

Mental Health

Prozac

Name: Prozac 20 mg (Fluoxetine)
Brand: Prozac
SKU: prozac
Availability: InStock

Fluoxetine · 20 mg · capsule · qty 30

SSRI for depression, OCD.

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Common uses & information

Prozac is a brand of Fluoxetine, a mental health medication supplied as capsule in a 20 mg strength. It is commonly used for sSRI for depression, OCD.

An FDA-approved generic (Fluoxetine) is available and typically costs less than the brand — compare both cash prices in the table above before you fill.

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Price summary

Form	Class	Brand avg	Generic avg	Savings
capsule 20 mg	Rx	$148.00 — generic is cheaper, see recommendation	$4.40Generic recommended	97%

Clinical information

Typical dosing

Typical adult dose: 20 mg once daily, range 20–80 mg.

Side effects

Insomnia, jitteriness, sexual side effects, GI upset.

Interactions to know

Do not combine with MAOIs. Strong CYP2D6 inhibitor — affects many other meds.

Pregnancy & breastfeeding

Risk-benefit discussion.

Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →

Manufacturer & patient assistance programs

For patient assistance, check NeedyMeds and RxAssist.

FAQ

Is generic Fluoxetine the same as Prozac?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

On average $143.60 per fill (97% off the brand price). Savings vary by pharmacy — see live prices above.

Do I need insurance to get this price?

No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.