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How much does Rheumatrex 2.5 mg cost without insurance?

As of August 2026, the lowest verified cash price for Rheumatrex 2.5 mg (Methotrexate) is $7.69 at Mark Cuban Cost Plus, based on 4 verified US pharmacy quotes. You don't need insurance to fill it, every price below is a real quote we verified, not an estimate or an insurance copay.

Pharmacy / sourceTypeVerified cash price
Mark Cuban Cost Pluspharmacy$7.69
Mark Cuban Cost Pluspharmacy$7.70
Honeybee Healthpharmacy$11.00
PlanetDrugsDirectpharmacy$50.99

Last verified Aug 21, 2026. Cash prices only, from verified public retail and mail-order sources, no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.

Common questions

What is the cheapest way to buy Rheumatrex 2.5 mg without insurance?
The lowest verified cash price we currently have for Rheumatrex 2.5 mg (Methotrexate) is $7.69 at Mark Cuban Cost Plus, from 4 verified pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
Is a generic version of Rheumatrex available?
Yes: Methotrexate is the generic of Rheumatrex and is what drives the low cash prices above.

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