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What is the generic of Rheumatrex?

The generic of Rheumatrex is Methotrexate. As of August 2026, the lowest verified cash price for Methotrexate 2.5 mg is $7.69 at Mark Cuban Cost Plus, based on 4 verified US pharmacy quotes, every price below is a real quote we verified, not an estimate.

Pharmacy / sourceTypeVerified cash price
Mark Cuban Cost Pluspharmacy$7.69
Mark Cuban Cost Pluspharmacy$7.70
Honeybee Healthpharmacy$11.00
PlanetDrugsDirectpharmacy$50.99

Last verified Aug 21, 2026. Cash prices only, from verified public retail and mail-order sources, no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.

Common questions

What is the generic of Rheumatrex?
The generic of Rheumatrex is Methotrexate. It contains the same active ingredient and is the version that drives the low cash prices below.
How much does generic Rheumatrex (Methotrexate) cost without insurance?
The lowest verified cash price we currently have for Methotrexate 2.5 mg is $7.69 at Mark Cuban Cost Plus, from 4 verified US pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
Is generic Methotrexate as effective as Rheumatrex?
Generic Methotrexate must meet the same FDA standards for active ingredient, strength, and quality as Rheumatrex. Ask your pharmacist if you have questions about switching.

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