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Amitiza

Generic Lubiprostone · capsule · Rx required · Treats chronic constipation and IBS-C.

Strength
Quantity

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The lowest verified cash price for Amitiza 24 mcg is $16.73 at Mark Cuban Cost Plus, based on 2 verified pharmacy prices checked August 22, 2026.

Local BetterBuy Rx prices near you

Enter your ZIP to check real pharmacy prices in your area with the free BetterBuy Rx discount card. No ZIP? The national price is in the results above.

How much does Amitiza cost without insurance?

The lowest verified cash price for Amitiza 24 mcg is $16.73 at Mark Cuban Cost Plus, based on 2 verified pharmacy prices checked August 22, 2026. Across 2 verified pharmacy prices, cash costs range from $16.73 to $128.99. These are cash prices, no insurance or signup is required, and for many generics the cash price beats a typical insurance copay. Prices vary by pharmacy, location, quantity, and eligibility; confirm the final price at the counter.

See the full Amitiza without-insurance price breakdown →

About Amitiza

Amitiza is a brand of Lubiprostone, a gi medication supplied as capsule in a 24 mcg strength. It is commonly used for treats chronic constipation and IBS-C.

Ways to save on Amitiza

Cash prices for Amitiza vary by pharmacy, location, quantity, and eligibility, so comparing a few pharmacies and checking whether a discount card beats your copay are the main ways to save. See the live prices above before you fill.

Manufacturer & patient assistance programs

For patient assistance, check NeedyMeds and RxAssist.

Frequently asked questions

How much does Amitiza cost without insurance?

The lowest verified cash price for Amitiza 24 mcg is $16.73 at Mark Cuban Cost Plus, based on 2 verified pharmacy prices checked August 22, 2026. These are cash prices, no insurance or signup needed, and refresh at least every 72 hours.

Is generic Lubiprostone the same as Amitiza?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

Currently no FDA-approved generic equivalent exists for Amitiza, so the brand and generic prices are similar.

Do I need insurance to get this price?

No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

Related medications

Compare Amitiza with other options and see the generic price.

Important safety information

Information for general comparison only. Not medical advice. Confirm with your pharmacist.