How much does Nucynta ER cost without insurance?

Live cash prices for Nucynta ER 100mg are verified within the last 72 hours — see the table above for the current cheapest source.

What pharmacy has the cheapest Nucynta ER?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Tapentadol ER. CVS and Walgreens are the most expensive. Exact rankings update live above.

Which pharmacy has the cheapest Nucynta ER in 2026?

GoodRx coupon currently has the lowest verified cash price for Nucynta ER (Tapentadol ER) at $0.00. Cost Plus Drugs and Costco are consistently the cheapest US pharmacies for most generics.

Is CVS or Walgreens cheaper for Nucynta ER?

Neither — both are typically 30–60% more expensive than Cost Plus or Costco. CVS and Walgreens consistently rank as the most expensive cash-pay pharmacies for Tapentadol ER.

How often do these prices change?

BetterBuyRx refreshes prices at minimum every 72 hours from public retail price feeds. Mail-order partners like Cost Plus and Amazon Pharmacy can change daily.

Pain

Nucynta ER

Name: Nucynta ER 100mg (Tapentadol ER)
Brand: Nucynta ER
SKU: nucynta-er
Availability: InStock

Tapentadol ER · 100mg · tablet · qty 60

Pain relief.

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Live verified prices

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Common uses & information

Nucynta ER is a brand of Tapentadol ER, a pain medication supplied as tablet in a 100mg strength. It is commonly used for pain relief.

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Price summary

Form	Class	Brand avg	Generic avg	Savings
tablet 100mg	Rx	$1244.53	see live prices above	—

Clinical information

Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →

Manufacturer & patient assistance programs

For patient assistance, check NeedyMeds and RxAssist.

FAQ

Is generic Tapentadol ER the same as Nucynta ER?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

Currently no FDA-approved generic equivalent exists for Nucynta ER, so the brand and generic prices are similar.

Do I need insurance to get this price?

No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.