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What is the generic of Zanaflex?

The generic of Zanaflex is Tizanidine. As of August 2026, the lowest verified cash price for Tizanidine 4 mg is $5.00 at Amazon Pharmacy RxPass, based on 13 verified US pharmacy quotes, every price below is a real quote we verified, not an estimate.

Pharmacy / sourceTypeVerified cash price
Amazon Pharmacy RxPassprogram$5.00
Amazon Pharmacy RxPassprogram$5.00
Mark Cuban Cost Pluspharmacy$5.62
Mark Cuban Cost Pluspharmacy$6.24
Honeybee Healthpharmacy$6.93
Honeybee Healthpharmacy$8.86

Last verified Aug 26, 2026. Cash prices only, from verified public retail and mail-order sources, no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.

Common questions

What is the generic of Zanaflex?
The generic of Zanaflex is Tizanidine. It contains the same active ingredient and is the version that drives the low cash prices below.
How much does generic Zanaflex (Tizanidine) cost without insurance?
The lowest verified cash price we currently have for Tizanidine 4 mg is $5.00 at Amazon Pharmacy RxPass, from 13 verified US pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
Is generic Tizanidine as effective as Zanaflex?
Generic Tizanidine must meet the same FDA standards for active ingredient, strength, and quality as Zanaflex. Ask your pharmacist if you have questions about switching.