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What is the generic of Zithromax Z-Pak?

The generic of Zithromax Z-Pak is Azithromycin. As of August 2026, the lowest verified cash price for Azithromycin 250 mg is $5.40 at Mark Cuban Cost Plus, based on 6 verified US pharmacy quotes, every price below is a real quote we verified, not an estimate.

Pharmacy / sourceTypeVerified cash price
Mark Cuban Cost Pluspharmacy$5.40
Mark Cuban Cost Pluspharmacy$5.88
Costco Pharmacypharmacy$6.49
BetterBuy Rxcoupon$9.07
Honeybee Healthpharmacy$29.00
PlanetDrugsDirectpharmacy$35.99

Last verified Aug 21, 2026. Cash prices only, from verified public retail and mail-order sources, no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.

Common questions

What is the generic of Zithromax Z-Pak?
The generic of Zithromax Z-Pak is Azithromycin. It contains the same active ingredient and is the version that drives the low cash prices below.
How much does generic Zithromax Z-Pak (Azithromycin) cost without insurance?
The lowest verified cash price we currently have for Azithromycin 250 mg is $5.40 at Mark Cuban Cost Plus, from 6 verified US pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
Is generic Azithromycin as effective as Zithromax Z-Pak?
Generic Azithromycin must meet the same FDA standards for active ingredient, strength, and quality as Zithromax Z-Pak. Ask your pharmacist if you have questions about switching.