Zithromax Z-Pak
Generic Azithromycin · tablet · Rx required · Respiratory & skin infections.
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The lowest verified cash price for Zithromax Z-Pak 250 mg is $5.40 at Mark Cuban Cost Plus, based on 6 verified pharmacy prices checked August 21, 2026.
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How much does Zithromax Z-Pak cost without insurance?
The lowest verified cash price for Zithromax Z-Pak 250 mg is $5.40 at Mark Cuban Cost Plus, based on 6 verified pharmacy prices checked August 21, 2026. Across 6 verified pharmacy prices, cash costs range from $5.40 to $35.99. These are cash prices, no insurance or signup is required, and for many generics the cash price beats a typical insurance copay. Prices vary by pharmacy, location, quantity, and eligibility; confirm the final price at the counter.
Zithromax Z-Pak is commonly dispensed as tablet in 250mg, 500mg, 100mg/5mL, 200mg/5mL strengths. Price varies by strength, quantity, and pharmacy, set your strength and quantity above to see the cash price for your exact fill.
See the full Zithromax Z-Pak without-insurance price breakdown →
About Zithromax Z-Pak
Zithromax Z-Pak is a brand of Azithromycin, a antibiotic medication supplied as tablet in a 250 mg strength. It is commonly used for respiratory & skin infections.
An FDA-approved generic (Azithromycin) is available and typically costs less than the brand, compare both cash prices in the results above before you fill.
Ways to save on Zithromax Z-Pak
Choosing the generic (Azithromycin) instead of the brand can lower your cost, on average about $82.60 per fill (90% off the brand price) in our catalog, though the exact price varies by pharmacy, location, quantity, and eligibility. Compare the live cash and discount prices above, and ask about a 90-day supply if you take it long-term.
Related savings guides
Clinical information
Typical dosing
Z-Pak: 500 mg day 1, then 250 mg days 2-5.
Side effects
Diarrhea, nausea, abdominal pain. Rare: QT prolongation.
Interactions to know
Caution with other QT-prolonging drugs and certain anticoagulants.
Pregnancy & breastfeeding
Generally considered low-risk.
Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →
Frequently asked questions
How much does Zithromax Z-Pak cost without insurance?
The lowest verified cash price for Zithromax Z-Pak 250 mg is $5.40 at Mark Cuban Cost Plus, based on 6 verified pharmacy prices checked August 21, 2026. These are cash prices, no insurance or signup needed, and refresh at least every 72 hours.
Is generic Azithromycin the same as Zithromax Z-Pak?
Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.
How much can I save by choosing the generic?
On average $82.60 per fill (90% off the brand price). Savings vary by pharmacy, see live prices above.
Do I need insurance to get this price?
No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.
How often is this price updated?
At minimum every 72 hours. Many sources refresh every few hours.
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Important safety information
Information for general comparison only. Not medical advice. Confirm with your pharmacist.