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How much does Nexium 24HR 20 mg cost without insurance?

As of August 2026, the lowest verified cash price for Nexium 24HR 20 mg (Esomeprazole) is $6.16 at Mark Cuban Cost Plus, based on 5 verified US pharmacy quotes. You don't need insurance to fill it, every price below is a real quote we verified, not an estimate or an insurance copay.

Pharmacy / sourceTypeVerified cash price
Mark Cuban Cost Pluspharmacy$6.16
Mark Cuban Cost Pluspharmacy$8.40
Costco Pharmacypharmacy$9.99
Honeybee Healthpharmacy$17.00
HealthWarehousepharmacy$30.60

Last verified Aug 23, 2026. Cash prices only, from verified public retail and mail-order sources, no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.

Common questions

What is the cheapest way to buy Nexium 24HR 20 mg without insurance?
The lowest verified cash price we currently have for Nexium 24HR 20 mg (Esomeprazole) is $6.16 at Mark Cuban Cost Plus, from 5 verified pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
Is a generic version of Nexium 24HR available?
Nexium 24HR is dispensed as Esomeprazole. Cash prices above reflect what US pharmacies verified most recently.

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