Nexium 24HR
Generic Esomeprazole · tablet · Rx required · See prescribing information.
Fetching live prices…
The lowest verified cash price for Nexium 24HR 20 mg is $6.16 at Mark Cuban Cost Plus, based on 5 verified pharmacy prices checked August 23, 2026.
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How much does Nexium 24HR cost without insurance?
The lowest verified cash price for Nexium 24HR 20 mg is $6.16 at Mark Cuban Cost Plus, based on 5 verified pharmacy prices checked August 23, 2026. Across 5 verified pharmacy prices, cash costs range from $6.16 to $30.60. These are cash prices, no insurance or signup is required, and for many generics the cash price beats a typical insurance copay. Prices vary by pharmacy, location, quantity, and eligibility; confirm the final price at the counter.
See the full Nexium 24HR without-insurance price breakdown →
About Nexium 24HR
Nexium 24HR is a brand of Esomeprazole, a other medication supplied as tablet in a 20 mg strength. It is commonly used for see prescribing information.
An FDA-approved generic (Esomeprazole) is available and typically costs less than the brand, compare both cash prices in the results above before you fill.
Ways to save on Nexium 24HR
Choosing the generic (Esomeprazole) instead of the brand can lower your cost, on average about $832.47 per fill (97% off the brand price) in our catalog, though the exact price varies by pharmacy, location, quantity, and eligibility. Compare the live cash and discount prices above, and ask about a 90-day supply if you take it long-term.
Don't pay for the Nexium 24HR label
Active ingredient: Esomeprazole magnesium 20mg
- ✓CVS Health Esomeprazole
- ✓Walgreens Wal-Somp
- ✓Equate Esomeprazole
Active ingredients are taken from the FDA Drug Facts panel (DailyMed). Store-brand prices are typical US shelf estimates and vary by location. Ask the pharmacist if you can't spot the store-brand version.
Other brands of Esomeprazole
Same active ingredient, different brand. Compare prices.
Frequently asked questions
How much does Nexium 24HR cost without insurance?
The lowest verified cash price for Nexium 24HR 20 mg is $6.16 at Mark Cuban Cost Plus, based on 5 verified pharmacy prices checked August 23, 2026. These are cash prices, no insurance or signup needed, and refresh at least every 72 hours.
Is generic Esomeprazole the same as Nexium 24HR?
Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.
How much can I save by choosing the generic?
On average $832.47 per fill (97% off the brand price). Savings vary by pharmacy, see live prices above.
Do I need insurance to get this price?
No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.
How often is this price updated?
At minimum every 72 hours. Many sources refresh every few hours.
Related medications
Compare Nexium 24HR with other options and see the generic price.
Cheapest Nexium 24HR alternatives
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Important safety information
Information for general comparison only. Not medical advice. Confirm with your pharmacist.