What is the generic of Nexium 24HR?
The generic of Nexium 24HR is Esomeprazole. As of August 2026, the lowest verified cash price for Esomeprazole 20 mg is $6.16 at Mark Cuban Cost Plus, based on 5 verified US pharmacy quotes, every price below is a real quote we verified, not an estimate.
| Pharmacy / source | Type | Verified cash price |
|---|---|---|
| Mark Cuban Cost Plus | pharmacy | $6.16 |
| Mark Cuban Cost Plus | pharmacy | $8.40 |
| Costco Pharmacy | pharmacy | $9.99 |
| Honeybee Health | pharmacy | $17.00 |
| HealthWarehouse | pharmacy | $30.60 |
Last verified Aug 23, 2026. Cash prices only, from verified public retail and mail-order sources, no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.
Common questions
- What is the generic of Nexium 24HR?
- The generic of Nexium 24HR is Esomeprazole. It contains the same active ingredient and is the version that drives the low cash prices below.
- How much does generic Nexium 24HR (Esomeprazole) cost without insurance?
- The lowest verified cash price we currently have for Esomeprazole 20 mg is $6.16 at Mark Cuban Cost Plus, from 5 verified US pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
- Is generic Esomeprazole as effective as Nexium 24HR?
- Generic Esomeprazole must meet the same FDA standards for active ingredient, strength, and quality as Nexium 24HR. Ask your pharmacist if you have questions about switching.