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How much does Zoloft 50 mg cost without insurance?

As of July 2026, the lowest verified cash price for Zoloft 50 mg (Sertraline) is $4.96 at BetterBuy Rx, based on 37 verified US pharmacy quotes. You don't need insurance to fill it — every price below is a real quote we verified, not an estimate or an insurance copay.

Pharmacy / sourceTypeVerified cash price
BetterBuy Rxcoupon$4.96
Amazon Pharmacy RxPassprogram$5.00
Amazon Pharmacy RxPassprogram$5.00
Amazon Pharmacy RxPassprogram$5.00
Amazon Pharmacy RxPassprogram$5.00
BetterBuy Rxcoupon$5.67

Last verified Jul 19, 2026. Cash prices only, from verified public retail and mail-order sources — no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.

Common questions

What is the cheapest way to buy Zoloft 50 mg without insurance?
The lowest verified cash price we currently have for Zoloft 50 mg (Sertraline) is $4.96 at BetterBuy Rx, from 37 verified pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
Is a generic version of Zoloft available?
Yes — Sertraline is the generic of Zoloft and is what drives the low cash prices above.