What is the generic of Zoloft?
The generic of Zoloft is Sertraline. As of July 2026, the lowest verified cash price for Sertraline 50 mg is $4.96 at BetterBuy Rx, based on 37 verified US pharmacy quotes — every price below is a real quote we verified, not an estimate.
| Pharmacy / source | Type | Verified cash price |
|---|---|---|
| BetterBuy Rx | coupon | $4.96 |
| Amazon Pharmacy RxPass | program | $5.00 |
| Amazon Pharmacy RxPass | program | $5.00 |
| Amazon Pharmacy RxPass | program | $5.00 |
| Amazon Pharmacy RxPass | program | $5.00 |
| BetterBuy Rx | coupon | $5.67 |
Last verified Jul 19, 2026. Cash prices only, from verified public retail and mail-order sources — no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.
Common questions
- What is the generic of Zoloft?
- The generic of Zoloft is Sertraline. It contains the same active ingredient and is the version that drives the low cash prices below.
- How much does generic Zoloft (Sertraline) cost without insurance?
- The lowest verified cash price we currently have for Sertraline 50 mg is $4.96 at BetterBuy Rx, from 37 verified US pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
- Is generic Sertraline as effective as Zoloft?
- Generic Sertraline must meet the same FDA standards for active ingredient, strength, and quality as Zoloft. Ask your pharmacist if you have questions about switching.