How much does Saphris cost without insurance?

Saphris (Asenapine) 5mg costs around $683.71 cash for the generic and $1176.61 for the brand. Live prices on this page are verified within the last 72 hours.

What pharmacy has the cheapest Saphris?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Asenapine. CVS and Walgreens are the most expensive. Exact rankings update live above.

Mental Health

Saphris

Name: Saphris 5mg (Asenapine)
Brand: Saphris
SKU: saphris-secuado
Availability: InStock

Asenapine · 5mg · tablet · qty 60

Depression, anxiety, or mood disorders.

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Common uses & information

Saphris is a brand of Asenapine, a mental health medication supplied as tablet in a 5mg strength. It is commonly used for depression, anxiety, or mood disorders.

An FDA-approved generic (Asenapine) is available and typically costs less than the brand — compare both cash prices in the table above before you fill.

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Price summary

Form	Class	Brand avg	Generic avg	Savings
tablet 5mg	Rx	$1176.61 — generic is cheaper, see recommendation	$683.71Generic recommended	42%

Clinical information

Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →

Manufacturer & patient assistance programs

For patient assistance, check NeedyMeds and RxAssist.

FAQ

Is generic Asenapine the same as Saphris?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

On average $492.90 per fill (42% off the brand price). Savings vary by pharmacy — see live prices above.

Do I need insurance to get this price?

No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.