What is the generic of Zofran?
The generic of Zofran is Ondansetron. As of August 2026, the lowest verified cash price for Ondansetron 4 mg is $5.00 at Amazon Pharmacy RxPass, based on 6 verified US pharmacy quotes, every price below is a real quote we verified, not an estimate.
| Pharmacy / source | Type | Verified cash price |
|---|---|---|
| Amazon Pharmacy RxPass | program | $5.00 |
| Honeybee Health | pharmacy | $6.00 |
| Mark Cuban Cost Plus | pharmacy | $6.17 |
| Mark Cuban Cost Plus | pharmacy | $6.28 |
| PlanetDrugsDirect | pharmacy | $42.99 |
| RxConnected.com | pharmacy | $76.00 |
Last verified Aug 22, 2026. Cash prices only, from verified public retail and mail-order sources, no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.
Common questions
- What is the generic of Zofran?
- The generic of Zofran is Ondansetron. It contains the same active ingredient and is the version that drives the low cash prices below.
- How much does generic Zofran (Ondansetron) cost without insurance?
- The lowest verified cash price we currently have for Ondansetron 4 mg is $5.00 at Amazon Pharmacy RxPass, from 6 verified US pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
- Is generic Ondansetron as effective as Zofran?
- Generic Ondansetron must meet the same FDA standards for active ingredient, strength, and quality as Zofran. Ask your pharmacist if you have questions about switching.