Skip to main content
Not medical advice · Terms & Privacy
BetterBuyRx

GI

Zofran

Ondansetron · 4 mg · tablet · qty 30

Anti-nausea.

See live generic prices →🔔 Price alert

Live verified prices

Fetching live quotes…

Common uses & information

Zofran is a brand of Ondansetron, a gi medication supplied as tablet in a 4 mg strength. It is commonly used for anti-nausea.

An FDA-approved generic (Ondansetron) is available and typically costs less than the brand — compare both cash prices in the table above before you fill.

Got questions?

Chat available now

Want to dig deeper on Zofran 4 mg?

Ask about generic alternatives, coverage, dosing, or have an agent widen the search to other pharmacies near you.

Price summary

FormClassBrand avgGeneric avgSavings
tablet 4 mgRx$312.00 — generic is cheaper, see recommendation$7.20Generic recommended98%

Clinical information

Typical dosing

Typical adult dose: 4–8 mg by mouth every 8 hours as needed, or as directed by your prescriber.

Side effects

Common: headache, constipation, tiredness. Serious (rare): QT prolongation (irregular heartbeat), serotonin syndrome when combined with other serotonergic drugs.

Interactions to know

Caution with other drugs that prolong the QT interval, and with other serotonergic medications (e.g. SSRIs, tramadol) due to serotonin syndrome risk.

Pregnancy & breastfeeding

FDA Pregnancy Category B. Widely used off-label for nausea in pregnancy. Some studies suggested a small association with cleft palate in the first trimester; larger studies have not confirmed increased birth defect risk. Discuss with your OB or midwife before use — do not self-prescribe.

Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →

Manufacturer & patient assistance programs

For patient assistance, check NeedyMeds and RxAssist.

FAQ

Is generic Ondansetron the same as Zofran?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

On average $304.80 per fill (98% off the brand price). Savings vary by pharmacy — see live prices above.

Do I need insurance to get this price?

No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

Related medications

Compare Zofran with other options and see the generic price.

See generic Ondansetron prices →
Acid reflux medications →

Other drugs for Acid reflux

Cheapest Zofran alternatives

Compare Zofran with…

Save more on Zofran

Information for general comparison only. Not medical advice. Confirm with your pharmacist.