How much does Prozac cost without insurance?

Prozac (Fluoxetine) 20 mg costs around $4.40 cash for the generic and $148.00 for the brand. Live prices on this page are verified within the last 72 hours.

What pharmacy has the cheapest Prozac?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Fluoxetine. CVS and Walgreens are the most expensive. Exact rankings update live above.

Which pharmacy has the cheapest Prozac in 2026?

Mark Cuban Cost Plus currently has the lowest verified cash price for Prozac (Fluoxetine) at $2.42. Cost Plus Drugs and Costco are consistently the cheapest US pharmacies for most generics.

Is CVS or Walgreens cheaper for Prozac?

Neither — both are typically 30–60% more expensive than Cost Plus or Costco. CVS and Walgreens consistently rank as the most expensive cash-pay pharmacies for Fluoxetine.

How often do these prices change?

BetterBuyRx refreshes prices at minimum every 72 hours from public retail price feeds. Mail-order partners like Cost Plus and Amazon Pharmacy can change daily.

Mental Health

Prozac

Name: Prozac 20 mg (Fluoxetine)
Brand: Prozac
SKU: prozac
Availability: InStock

Fluoxetine · 20 mg · capsule · qty 30

SSRI for depression, OCD.

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Live verified prices

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Common uses & information

Prozac is a brand of Fluoxetine, a mental health medication supplied as capsule in a 20 mg strength. It is commonly used for sSRI for depression, OCD.

An FDA-approved generic (Fluoxetine) is available and typically costs less than the brand — compare both cash prices in the table above before you fill.

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Want to dig deeper on Prozac 20 mg?

Ask about generic alternatives, coverage, dosing, or have an agent widen the search to other pharmacies near you.

Price summary

Form	Class	Brand avg	Generic avg	Savings
capsule 20 mg	Rx	$148.00 — generic is cheaper, see recommendation	$4.40Generic recommended	97%

Clinical information

Typical dosing

Typical adult dose: 20 mg once daily, range 20–80 mg.

Side effects

Insomnia, jitteriness, sexual side effects, GI upset.

Interactions to know

Do not combine with MAOIs. Strong CYP2D6 inhibitor — affects many other meds.

Pregnancy & breastfeeding

Risk-benefit discussion.

Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →

Manufacturer & patient assistance programs

For patient assistance, check NeedyMeds and RxAssist.

FAQ

Is generic Fluoxetine the same as Prozac?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

On average $143.60 per fill (97% off the brand price). Savings vary by pharmacy — see live prices above.

Do I need insurance to get this price?

No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

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Compare Prozac with other options and see the generic price.

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.