How much does Wellbutrin XL cost without insurance?

Wellbutrin XL (Bupropion) 300 mg costs around $18.40 cash for the generic and $398.00 for the brand. Live prices on this page are verified within the last 72 hours.

What pharmacy has the cheapest Wellbutrin XL?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Bupropion. CVS and Walgreens are the most expensive. Exact rankings update live above.

Which pharmacy has the cheapest Wellbutrin XL in 2026?

Costco Pharmacy currently has the lowest verified cash price for Wellbutrin XL (Bupropion) at $11.41. Cost Plus Drugs and Costco are consistently the cheapest US pharmacies for most generics.

Is CVS or Walgreens cheaper for Wellbutrin XL?

Neither — both are typically 30–60% more expensive than Cost Plus or Costco. CVS and Walgreens consistently rank as the most expensive cash-pay pharmacies for Bupropion.

How often do these prices change?

BetterBuyRx refreshes prices at minimum every 72 hours from public retail price feeds. Mail-order partners like Cost Plus and Amazon Pharmacy can change daily.

Mental Health

Wellbutrin XL

Name: Wellbutrin XL 300 mg (Bupropion)
Brand: Wellbutrin XL
SKU: wellbutrin-xl
Availability: InStock

Bupropion · 300 mg · tablet · qty 30

NDRI, extended-release (once daily); depression, smoking cessation. Distinct from Wellbutrin SR (twice-daily) and immediate-release bupropion (three-times-daily) -- not interchangeable without prescriber guidance.

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Common uses & information

Wellbutrin XL is a brand of Bupropion, a mental health medication supplied as tablet in a 300 mg strength. It is commonly used for nDRI, extended-release (once daily); depression, smoking cessation. Distinct from Wellbutrin SR (twice-daily) and immediate-release bupropion (three-times-daily) -- not interchangeable without prescriber guidance.

An FDA-approved generic (Bupropion) is available and typically costs less than the brand — compare both cash prices in the table above before you fill.

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Price summary

Form	Class	Brand avg	Generic avg	Savings
tablet 300 mg	Rx	$398.00 — generic is cheaper, see recommendation	$18.40Generic recommended	95%

Clinical information

Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →

Manufacturer & patient assistance programs

NeedyMeds Wellbutrin XL Patient Assistance
Directory listing of manufacturer and foundation assistance options for Wellbutrin XL; a generic (bupropion XL) is also FDA-approved and usually far cheaper.
Enroll →

FAQ

Is generic Bupropion the same as Wellbutrin XL?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

On average $379.60 per fill (95% off the brand price). Savings vary by pharmacy — see live prices above.

Do I need insurance to get this price?

No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

Related medications

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.