How much does Zulresso cost without insurance?

Live cash prices for Zulresso 100mg/20mL are verified within the last 72 hours — see the table above for the current cheapest source.

What pharmacy has the cheapest Zulresso?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Brexanolone. CVS and Walgreens are the most expensive. Exact rankings update live above.

How does a Zulresso discount card work?

Show the discount card barcode to your pharmacist at checkout. They run it instead of insurance, and the cash price is reduced. No signup, no email, no insurance card needed.

Is the Zulresso discount card really free?

Yes — the GoodRx card is free forever. BetterBuyRx makes no money on coupons. We also compare the card price to direct cash prices at Cost Plus and Costco, which are sometimes lower.

Mental Health

Zulresso

Name: Zulresso 100mg/20mL (Brexanolone)
Brand: Zulresso
SKU: zulresso
Availability: InStock

Brexanolone · 100mg/20mL · injection · qty 1

Depression, anxiety, or mood disorders.

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Live verified prices

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Common uses & information

Zulresso is a brand of Brexanolone, a mental health medication supplied as injection in a 100mg/20mL strength. It is commonly used for depression, anxiety, or mood disorders.

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Price summary

Form	Class	Brand avg	Generic avg	Savings
injection 100mg/20mL	Rx	see live prices above	see live prices above	—

Clinical information

Clinical content reviewed by the BetterBuyRx clinical team. Read the full wiki entry and sources →

Manufacturer & patient assistance programs

For patient assistance, check NeedyMeds and RxAssist.

FAQ

Is generic Brexanolone the same as Zulresso?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

Currently no FDA-approved generic equivalent exists for Zulresso, so the brand and generic prices are similar.

Do I need insurance to get this price?

No. The prices shown on BetterBuyRx are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

Related medications

Compare Zulresso with other options and see the generic price.

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.