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What is the generic of Effexor XR?

The generic of Effexor XR is Venlafaxine. As of August 2026, the lowest verified cash price for Venlafaxine 75 mg is $5.00 at Amazon Pharmacy RxPass, based on 6 verified US pharmacy quotes, every price below is a real quote we verified, not an estimate.

Pharmacy / sourceTypeVerified cash price
Amazon Pharmacy RxPassprogram$5.00
Mark Cuban Cost Pluspharmacy$6.97
Honeybee Healthpharmacy$8.00
Costco Pharmacypharmacy$8.49
Blink Healthpharmacy$8.90
PlanetDrugsDirectpharmacy$45.99

Last verified Aug 21, 2026. Cash prices only, from verified public retail and mail-order sources, no insurance copays, no estimates, no extrapolation across strengths or quantities. Prices change; confirm at the pharmacy counter. See our methodology.

Common questions

What is the generic of Effexor XR?
The generic of Effexor XR is Venlafaxine. It contains the same active ingredient and is the version that drives the low cash prices below.
How much does generic Effexor XR (Venlafaxine) cost without insurance?
The lowest verified cash price we currently have for Venlafaxine 75 mg is $5.00 at Amazon Pharmacy RxPass, from 6 verified US pharmacy quotes. Prices change; confirm at the pharmacy before you buy.
Is generic Venlafaxine as effective as Effexor XR?
Generic Venlafaxine must meet the same FDA standards for active ingredient, strength, and quality as Effexor XR. Ask your pharmacist if you have questions about switching.