Type 2 Diabetes medication prices (2026)
Type 2 diabetes is treated with oral medications (metformin, sulfonylureas, DPP-4 inhibitors, SGLT2 inhibitors) and injectable GLP-1 agonists. Cash prices for older generics like metformin are under $10/month; brand GLP-1s like Ozempic and Mounjaro can exceed $1,000/month without insurance.
All Diabetes medications ranked by cash price
| Brand | Generic | Strength | Generic cash | Brand cash |
|---|---|---|---|---|
| Semglee | Insulin Glargine-yfgn | 100 units/mL | see live | see live |
| Lyumjev | Insulin Lispro-aabc | 100 units/mL | see live | see live |
| Invokana | Canagliflozin | 100 mg | see live | see live |
| DiaBeta | Glyburide | 5 mg | see live | see live |
| Prandin | Repaglinide | 1 mg | see live | see live |
| Nesina | Alogliptin | 25 mg | see live | see live |
| Byetta | Exenatide | 10 mcg/dose | see live | see live |
| Tresiba | Insulin Degludec | 100 units/mL | see live | see live |
| Humulin N | Insulin Isophane | 100 units/mL | see live | see live |
| Humulin R | Insulin Regular | 100 units/mL | see live | see live |
| Adlyxin | Lixisenatide | 20mcg | see live | see live |
| Afrezza | Insulin Human Inhaled | 8 units | see live | $2041.72 |
| Avandia | Rosiglitazone | 4mg | see live | see live |
| Brenzavvy | Bexagliflozin | 20mg | see live | see live |
| Fiasp | Insulin Aspart Ultra Fast | 100 units/mL | see live | $768.97 |
| Glyxambi | Empagliflozin/Linagliptin | 10mg/5mg | see live | $583.77 |
| Humalog Mix 75/25 | Insulin Lispro Protamine 75/25 | 100 units/mL | see live | $259.93 |
| Humalog U-200 | Insulin Lispro U-200 | 200 units/mL | see live | see live |
| Humulin R U-500 | Insulin Regular U-500 | 500 units/mL | see live | $2123.12 |
| Invokamet | Canagliflozin/Metformin | 150mg/500mg | see live | $279.34 |
| Janumet | Sitagliptin/Metformin | 50mg/1000mg | see live | $538.03 |
| Jentadueto | Linagliptin/Metformin | 2.5mg/1000mg | see live | $501.71 |
| Mitiglinide | Mitiglinide | 10mg | see live | see live |
| NovoLog Mix 70/30 | Insulin Aspart Mix 70/30 | 100 units/mL | see live | $229.80 |
| Steglatro | Ertugliflozin | 5mg | see live | $343.57 |
| Symlin | Pramlintide | 1000mcg/mL | see live | $1711.19 |
| Synjardy | Empagliflozin/Metformin | 12.5mg/1000mg | see live | $288.28 |
| Tanzeum | Albiglutide | 30mg | see live | see live |
| Toujeo | Insulin Glargine U-300 | 300 units/mL | see live | $720.84 |
| Tresiba U-200 | Insulin Degludec U-200 | 200 units/mL | see live | see live |
| Tzield | Teplizumab | 2mg/2mL | see live | see live |
| Xigduo XR | Dapagliflozin/Metformin | 10mg/1000mg | see live | $408.22 |
| Glucophage | Metformin | 500 mg | $4.00 | $89.00 |
| Amaryl | Glimepiride | 2 mg | $4.80 | $68.00 |
| Glucotrol | Glipizide | 10 mg | $5.40 | $72.00 |
| Actos | Pioglitazone | 30 mg | $12.40 | $148.00 |
| Actoplus Met | Pioglitazone/Metformin | 15mg/850mg | $14.40 | $572.08 |
| Precose | Acarbose | 50 mg | $24.00 | $128.00 |
| Starlix | Nateglinide | 120mg | $30.56 | $30.56 |
| Lantus | Insulin Glargine | 100 units/mL | $68.00 | $284.00 |
| Levemir | Insulin Detemir | 100 units/mL | $72.00 | $289.00 |
| Humalog | Insulin Lispro | 100 units/mL | $78.50 | $332.00 |
| NovoLog | Insulin Aspart | 100 units/mL | $82.00 | $328.00 |
| Glyset | Miglitol | 50mg | $155.96 | $155.96 |
| Kombiglyze XR | Saxagliptin/Metformin XR | 5mg/1000mg | $159.19 | $343.00 |
| Januvia | Sitagliptin | 100 mg | $289.00 | $612.00 |
| Onglyza | Saxagliptin | 5 mg | $468.00 | $512.00 |
| Farxiga | Dapagliflozin | 10 mg | $592.00 | $612.00 |
| Jardiance | Empagliflozin | 25 mg | $628.00 | $648.00 |
| Victoza | Liraglutide | 1.8 mg/dose | $780.00 | $812.00 |
| Trulicity | Dulaglutide | 1.5 mg/dose | $860.00 | $892.00 |
| Ozempic | Semaglutide | 1 mg/dose | $920.00 | $968.00 |
| Mounjaro | Tirzepatide | 5 mg/dose | $1020.00 | $1069.00 |
FAQ
What is the cheapest medication for Diabetes?
Generic Insulin Glargine-yfgn (Semglee) averages $0.00 cash. Cost Plus and Costco usually have the lowest verified prices.
Can I fill Diabetes medications without insurance?
Yes. Every drug on this page can be filled cash-pay at any US pharmacy. Generic versions are usually under $15/month at Cost Plus, Costco, or with a GoodRx coupon.
Are generic Diabetes drugs as good as brand?
Yes, the FDA requires generics to contain the same active ingredient at the same strength as the brand and to be therapeutically equivalent.